Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116302 | 0.90 | CHEK2 (0.42) | BRD4KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL28116286 | 0.87 | MAPT (0.43) | BRD4KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8818754 | 0.83 | PARP1 (0.54) | BRD4CHEK1NEK2LIMK1TYRO3 | |
| SCHEMBL28116660 | 0.76 | PARP1 (0.40) | KDM4EALDH1A1MAPTPARP1TP53 | |
| SCHEMBL8818589 | 0.72 | PARP1 (0.55) | BRD4MAPTPARP1TP53ALOX5 | |
| SCHEMBL8891814 | 0.72 | PARP1 (0.57) | BRD4KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8817568 | 0.72 | PARP1 (0.54) | MAPTPARP1TP53GAADHFR | |
| SCHEMBL8814833 | 0.71 | PARP1 (0.53) | TSHRMAPTPARP1TP53MEN1 | |
| SCHEMBL17251750 | 0.71 | MAPT (0.50) | BRD4KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL28116288 | 0.70 | PARP1 (0.53) | MAPTPARP1TP53CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |