Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116302 | 0.88 | CHEK2 (0.42) | MAPTBRD4TP53LMNANPSR1 | |
| SCHEMBL28116659 | 0.87 | BRD4 (0.43) | MAPTBRD4TP53LMNANPSR1 | |
| SCHEMBL8818794 | 0.82 | PARP1 (0.56) | MAPTBRD4TP53LMNANPSR1 | |
| SCHEMBL28116660 | 0.79 | PARP1 (0.40) | MAPTTP53AMY1APARP1SMN1; SMN2 | |
| SCHEMBL17251750 | 0.75 | MAPT (0.50) | MAPTBRD4TP53LMNANPSR1 | |
| SCHEMBL28116288 | 0.74 | PARP1 (0.53) | MAPTTP53PARP1GUSBCYP1A2 | |
| SCHEMBL7917574 | 0.73 | ALDH1A1 (0.61) | MAPTTP53LMNANPSR1AMY1A | |
| SCHEMBL8817577 | 0.72 | PARP1 (0.58) | MAPTBRD4TP53LMNANPSR1 | |
| SCHEMBL28116663 | 0.72 | KDM4E (0.47) | MAPTTP53LMNANPSR1HTT | |
| SCHEMBL8891814 | 0.71 | PARP1 (0.57) | MAPTBRD4TP53LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |