Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 10/20 | 0.47 |
| ▸ | TUBB | P07437 | 10/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 10/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 10/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 10/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 10/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 10/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13356593 | 0.83 | HTT (0.56) | MAPTNPSR1HTTTUBB4ATUBB | |
| SCHEMBL1617954 | 0.77 | ERN1 (0.64) | MAPTHTTTUBB4ATUBBTUBA3C | |
| SCHEMBL29466480 | 0.77 | HTT (0.62) | MAPTSMN1; SMN2HTTTUBB4ATUBB | |
| SCHEMBL28116661 | 0.76 | PARP1 (0.48) | MAPTTP53SMN1; SMN2TUBB4ATUBB | |
| SCHEMBL1616441 | 0.76 | HTT (0.57) | MAPTSMN1; SMN2HTTTUBB4ATUBB | |
| SCHEMBL1618022 | 0.76 | HTT (0.60) | MAPTNPSR1HTTTUBB4ATUBB | |
| SCHEMBL10316385 | 0.76 | HTT (0.57) | MAPTSMN1; SMN2HTTTUBB4ATUBB | |
| SCHEMBL23736317 | 0.75 | POLB (0.53) | SMN1; SMN2HTTATMMEN1NPC1 | |
| SCHEMBL13931944 | 0.75 | TUBB4A (0.67) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28384562 | 0.73 | AAK1 (0.54) | MAPTTP53SMN1; SMN2NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |