Pyridine

Pyridine

SCHEMBL28116713

OC(=S)n1cccc1.[LiH].c1ccncc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
FBP1 P09467 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28258663 0.82
Pyridine SCHEMBL28114825 0.78 NAPRT (0.45) TSHRNAPRTTDP1FBP1
Pyridine SCHEMBL28080633 0.76 TSHR (0.43) TSHRNAPRTTDP1FBP1
Pyridine SCHEMBL6532110 0.69
Pyridine SCHEMBL28067297 0.69 NAPRT (0.90) TSHRNAPRTTDP1
Pyridine SCHEMBL6154203 0.69
Pyridine SCHEMBL9903903 0.69
Pyridine SCHEMBL28207163 0.69 TSHR (0.53) TSHRNAPRTTDP1
Pyridine SCHEMBL28166195 0.69 TSHR (0.53) TSHRNAPRTTDP1
SCHEMBL31062008 0.68 NAPRT (0.45) TSHRNAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106163526-A Treatment of resistant acne 维奥姆生物科学有限公司 2016-11-23 CN disclosed