⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28067297 | 1.00 | NAPRT (0.90) | — | |
| Pyridine SCHEMBL2348132 | 0.95 | NAPRT (0.82) | — | |
| Pyridine SCHEMBL15309118 | 0.95 | NAPRT (0.82) | — | |
| Pyridine SCHEMBL3694611 | 0.95 | NAPRT (0.82) | — | |
| Pyridine SCHEMBL28910607 | 0.95 | NAPRT (0.82) | — | |
| Pyridine SCHEMBL1206485 | 0.95 | — | — | |
| Pyridine SCHEMBL933604 | 0.95 | TSHR (1.00) | — | |
| Pyridine SCHEMBL16 | 0.95 | — | — | |
| Benzene SCHEMBL1261317 | 0.95 | TSHR (1.00) | — | |
| SCHEMBL3052767 | 0.95 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224662-B1 | PROCESS FOR THE PREPARATION OF OXIDES OF AROMATIC TERTIARY AMINES, AND PRODUCTS SO OBTAINED | INTEROX Société Anonyme (BE) | 1991-12-18 | — | — | EP | claimed |
| CN-106243021-A | A kind of method of synthesis 4 aminopyridines | 南京红太阳生物化学有限责任公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-1216637-C | Pharmaceutical composition containing an inhibitor of immunoglobulin-receptor interaction | TECNOGEN SCPA (IT) | 2005-08-31 | — | — | CN | disclosed |
| US-6861529-B2 | Cycloalkylpyrrole-3-carboxylic acid amide derivatives and heterocycloalkylpyrrole-3-carboxylic acid amide derivatives that bind with high affinity to the benzodiazepine site of GABA-A (gamma-aminobutyric acid) receptors | PFIZER INC (US) | 2005-03-01 | — | — | US | disclosed |
| EP-1404316-A1 | CYCLOALKYLPYRROLE-3-CARBOXYLIC ACID DERIVATIVES AND HETEROCYCLOALKYLPYRROLE-3-CARBOXYLIC ACID DERIVATIVES AS GABA-A RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| US-20030069416-A1 | Cycloalkylpyrrole-3-carboxylic acid derivatives and heterocycloalkylpyrrole-3-carboxylic acid derivatives | PFIZER INC. | 2003-04-10 | — | — | US | disclosed |
| WO-2003004018-A1 | CYCLOALKYLPYRROLE-3-CARBOXYLIC ACID DERIVATIVES AND HETEROCYCLOALKYLPYRROLE-3-CARBOXYLIC ACID DERIVATIVES AS GABA-A RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2003-01-16 | — | — | WO | disclosed |
| CN-1240357-A | Pharmaceutical compositions comprising inhibitors of immunoglobulin-receptor interactions | TECNOGEN SCPA (IT) | 2000-01-05 | — | — | CN | disclosed |