Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20758125 | 0.82 | HSD17B10 (0.67) | HSD17B10ALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL24628398 | 0.82 | KMT2A (0.59) | HSD17B10ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL25583882 | 0.82 | KLKB1 (0.51) | EPHB4TEKKCNH2ADORA2AADORA2B | |
| SCHEMBL710149 | 0.82 | LMNA (0.67) | ALDH1A1KDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL25583711 | 0.81 | TEK (0.47) | ALDH1A1KDM4EL3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL21492320 | 0.80 | LMNA (0.48) | ALDH1A1KDM4ELMNAMAPTEPHB4 | |
| SCHEMBL24208605 | 0.80 | TEK (0.46) | ALDH1A1KDM4EL3MBTL1LMNAMAPT | |
| SCHEMBL10249223 | 0.78 | EPHB4 (0.43) | HSD17B10ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL15661558 | 0.77 | HSD17B10 (0.66) | HSD17B10ALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL24871362 | 0.77 | HSD17B10 (0.61) | HSD17B10ALDH1A1KDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349087-B | Compounds and methods for inhibiting fascin | 康奈尔大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-111349087-A | Compounds and methods for inhibiting fascin | 康奈尔大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-106232583-B | Compounds and methods for inhibiting fascin | 康奈尔大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-106232583-A | Compounds and methods for inhibiting fascin | 康奈尔大学 | 2016-12-14 | — | — | CN | disclosed |