Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863382 | 0.85 | — | — | |
| SCHEMBL13641574 | 0.78 | CHRM2 (0.33) | CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9413711 | 0.76 | LMNA (0.39) | LMNA | |
| SCHEMBL5064655 | 0.75 | CHRM2 (0.31) | CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL3871855 | 0.72 | — | — | |
| SCHEMBL8631552 | 0.71 | TSHR (0.38) | LMNA | |
| Dioxane SCHEMBL7672675 | 0.71 | LMNA (0.67) | LMNA | |
| SCHEMBL1107592 | 0.71 | LMNA (0.46) | LMNA | |
| SCHEMBL7590839 | 0.69 | LMNA (0.55) | LMNA | |
| SCHEMBL15422679 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530063-B | Quinazoline and heterocyclic ring compounds, preparing method of compounds, and application of compounds serving as epidermal growth factor receptor inhibitors used for treating cancer | 北京赛特明强医药科技有限公司 | 2017-01-18 | — | — | CN | disclosed |