Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17076753 | 0.84 | MAPT (0.41) | MAPTLMNAL3MBTL1ALDH1A1PKM | |
| SCHEMBL1703493 | 0.78 | MAPT (0.42) | MAPTLMNAL3MBTL1ALDH1A1PKM | |
| SCHEMBL673074 | 0.78 | MAPT (0.42) | MAPTLMNAL3MBTL1ALDH1A1PKM | |
| SCHEMBL1662956 | 0.77 | CCNC (0.43) | MAPTLMNAL3MBTL1ALDH1A1PKM | |
| SCHEMBL21972021 | 0.77 | MAPT (0.36) | MAPTLMNAL3MBTL1ALDH1A1PKM | |
| SCHEMBL28206459 | 0.77 | GAA (0.35) | L3MBTL1ALPIALPGPLAA | |
| Hydrochloric Acid SCHEMBL1559285 | 0.76 | MAPT (0.45) | MAPTLMNAL3MBTL1ALDH1A1PKM | |
| SCHEMBL13739798 | 0.76 | MEN1 (0.42) | MAPTLMNAL3MBTL1ALDH1A1PKM | |
| SCHEMBL1703729 | 0.76 | CCNC (0.45) | MAPTLMNA | |
| SCHEMBL174144 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026397-B | As 9 (aryl or heteroaryl) 2 (pyrazolyl, pyrrolidinyl or cyclopenta) amino purine derivatives of anticancer | 默克专利股份公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-103930416-B | BENZONITRILE DERIVATIVES AS KINASE INHIBITORS | 默克专利股份公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-104066734-B | Triazol [4,5 d] pyrimidine derivatives | 默克专利股份公司 | 2017-03-29 | — | — | CN | disclosed |