SCHEMBL28206459

SCHEMBL28206459

C[C](C)Cn1cc(O)cn1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
ALPI P09923 1/20 0.35
ALPG P10696 1/20 0.35
PLAA Q9Y263 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5172952 0.77 HTT (0.40) GAAALPIALPGPLAAL3MBTL1
SCHEMBL28117286 0.77 MAPT (0.43) ALPIALPGPLAAL3MBTL1
SCHEMBL11623307 0.77
SCHEMBL16101449 0.74
SCHEMBL22657263 0.73
SCHEMBL2659213 0.71
SCHEMBL28163282 0.71 MEN1 (0.35) GAAALPIALPGPLAAL3MBTL1
SCHEMBL11084604 0.71 L3MBTL1 (0.44) GAAL3MBTL1
SCHEMBL27807996 0.70 LMNA (0.54) GAAL3MBTL1
SCHEMBL16100862 0.69 NAMPT (0.44) GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107690281-A Cystic fibrosis transmembrane transduction modulator modulators 弗特克斯药品有限公司 2018-02-13 CN disclosed