SCHEMBL28117296

SCHEMBL28117296

C=C(C(=O)O)C(C)(CBr)OC(C)=O

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
TET2 Q6N021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2465322 0.73 GAA (0.38) GAATET2
SCHEMBL28357690 0.70 TET2 (0.37) TET2
SCHEMBL2007257 0.69 GAA (0.40) GAA
SCHEMBL11342324 0.69 GAA (0.35) GAA
SCHEMBL503237 0.68
SCHEMBL7931339 0.67 GAA (0.37) GAA
SCHEMBL11024978 0.65 TET2 (0.33) TET2
SCHEMBL11534385 0.65 GAA (0.50) GAA
SCHEMBL4453703 0.64 TET2 (0.32) TET2
SCHEMBL10529337 0.64 GAA (0.48) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279128-B Epoxyethane derivative and preparation method thereof and application in medicine 四川海思科制药有限公司 2019-09-13 CN disclosed
CN-106279128-A Epoxyethane derivative and preparation method thereof and in application pharmaceutically 四川海思科制药有限公司 2017-01-04 CN disclosed