SCHEMBL7931339

SCHEMBL7931339

C=C(C(=O)O)C(C)(C#N)OC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8841242 0.81 GAA (0.37) GAA
SCHEMBL2465322 0.74 GAA (0.38) GAAHSD17B10TDP1
SCHEMBL8841250 0.73 DGAT1 (0.39) GAA
SCHEMBL11342324 0.71 GAA (0.35) GAAHSD17B10TDP1
SCHEMBL2007257 0.71 GAA (0.40) GAAHSD17B10TDP1
SCHEMBL10835420 0.69 MEN1 (0.44) GAAHSD17B10
SCHEMBL25201929 0.69 TET2 (0.33) TDP1
SCHEMBL6155938 0.69 GAA (0.41) GAAHSD17B10TDP1
SCHEMBL585284 0.69
SCHEMBL28117296 0.67 GAA (0.45) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6239207-B1 Active-methylene functionalized latex polymer prepared in the presence of a hydrophilic isoprene sulfuric acid polymer, and sheet material comprising same KONICA CORPORATION (JP) 2001-05-29 US disclosed