Acetone

Acetone

SCHEMBL28117313

CC(C)=O.c1ccc(C2CCCCC2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.58
SLC18A3 Q16572 8/20 0.53
LIPE Q05469 1/20 0.49
HAO1 Q9UJM8 1/20 0.49
TRPA1 O75762 1/20 0.49
AKR1C3 P42330 1/20 0.48
AKR1C1 Q04828 1/20 0.48
CYP2D6 P10635 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
SIGMAR1 Q99720 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
HIF1A Q16665 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7274837 0.94 KMO (0.55) KMOSLC18A3TRPA1AKR1C3AKR1C1
Bicarbonate SCHEMBL9436080 0.91 KMO (0.61) KMOSLC18A3HAO1AKR1C3AKR1C1
Bicarbonate SCHEMBL4410582 0.91 KMO (0.61) KMOSLC18A3HAO1AKR1C3AKR1C1
Bicarbonate SCHEMBL4407651 0.91 KMO (0.61) KMOSLC18A3HAO1AKR1C3AKR1C1
Methyl Alcohol SCHEMBL27426390 0.89 SLC18A3 (0.57) KMOSLC18A3TRPA1CYP2D6SMN1; SMN2
Bicarbonate SCHEMBL4412934 0.89 KMO (0.58) KMOSLC18A3HAO1TRPA1AKR1C3
Hydrogen Peroxide SCHEMBL9997756 0.89 SLC18A3 (0.61) KMOSLC18A3TRPA1CYP2D6SMN1; SMN2
Hydrogen Peroxide SCHEMBL5901852 0.89 SLC18A3 (0.61) KMOSLC18A3TRPA1CYP2D6SMN1; SMN2
Hydrogen Peroxide SCHEMBL11586135 0.89 SLC18A3 (0.61) KMOSLC18A3TRPA1CYP2D6SMN1; SMN2
Hydrogen Peroxide SCHEMBL42934 0.89 SLC18A3 (0.61) KMOSLC18A3TRPA1CYP2D6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108329243-A Polymer/metallic porphyrin and n-Hydroxyphthalimide concerted catalysis cyclohexylbenzene hydroperoxide 湖南大学 2018-07-27 CN disclosed
CN-106316913-A Process and reactor system for oxidizing cycloalkylbenzene 埃克森美孚化学专利公司 2017-01-11 CN disclosed