Diphenylamine

Diphenylamine

SCHEMBL28117645

Oc1ccccc1.S.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.70

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.70
TSHR P16473 4/20 0.70
HSD17B10 Q99714 5/20 0.67
ALDH1A1 P00352 7/20 0.63
TDP1 Q9NUW8 5/20 0.63
ALOX12 P18054 3/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
ALOX15 P16050 2/20 0.63
PTGS1 P23219 1/20 0.63
SLC6A2 P23975 1/20 0.63
MAPK1 P28482 1/20 0.63
PTGS2 P35354 1/20 0.63
HTR2B P41595 1/20 0.63
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
GLA P06280 1/20 0.61
CA3 P07451 1/20 0.61
CA4 P22748 1/20 0.61
CA9 Q16790 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL5867343 0.97 CYP3A4 (0.73) CYP3A4TSHRHSD17B10ALDH1A1TDP1
SCHEMBL3371479 0.89 ALDH1A1 (0.72) CYP3A4TSHRHSD17B10ALDH1A1TDP1
SCHEMBL585745 0.89 ALDH1A1 (0.72) CYP3A4TSHRHSD17B10ALDH1A1TDP1
SCHEMBL3369514 0.89 ALDH1A1 (0.72) CYP3A4TSHRHSD17B10ALDH1A1TDP1
SCHEMBL92754 0.89 ALDH1A1 (0.72) CYP3A4TSHRHSD17B10ALDH1A1TDP1
SCHEMBL27456694 0.86 ALDH1A1 (0.68) CYP3A4TSHRHSD17B10ALDH1A1TDP1
Diphenylamine SCHEMBL28222060 0.85 HSD17B10 (0.92) CYP3A4TSHRHSD17B10ALDH1A1TDP1
Diphenylamine SCHEMBL8360007 0.85 HSD17B10 (0.92) CYP3A4TSHRHSD17B10ALDH1A1TDP1
Diphenylamine SCHEMBL27879878 0.84 CYP3A4 (0.86) CYP3A4TSHRHSD17B10ALDH1A1TDP1
SCHEMBL29678179 0.82 CYP3A4 (1.00) CYP3A4TSHRHSD17B10ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103130833-B Soluble oxime ester and aromatic ketone photo polymerization initiator 深圳市有为化学技术有限公司 2017-02-08 CN disclosed