SCHEMBL28117745

SCHEMBL28117745

CCCCCC(CC)COC(=O)c1ccccc1C(=O)O

nearest known ligand 0.87

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.87
PRSS2 P07478 1/20 0.87
PRSS3 P35030 1/20 0.87
ALDH1A1 P00352 10/20 0.82
CYP3A4 P08684 5/20 0.82
CA2 P00918 1/20 0.82
LMNA P02545 4/20 0.70
TSHR P16473 8/20 0.61
MAPK1 P28482 4/20 0.61
TP53 P04637 1/20 0.54
TDP1 Q9NUW8 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
HSD17B10 Q99714 1/20 0.51
ATM Q13315 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
RECQL P46063 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28117428 0.99 PRSS1 (0.90) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL3772079 0.99 PRSS1 (0.90) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL29399469 0.96 ALDH1A1 (0.89) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
Bis(2-Ethylhexyl) Phthalate SCHEMBL28278055 0.96 ALDH1A1 (0.89) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL472689 0.96 ALDH1A1 (0.89) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL21114418 0.96 ALDH1A1 (0.89) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
Phthalic Acid SCHEMBL28278056 0.96 ALDH1A1 (0.89) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28396810 0.94 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL30532536 0.94 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL30532537 0.94 PRSS1 (0.97) PRSS1PRSS2PRSS3ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106380729-B Novel PVC heat stabilizer 邵卫东 2019-01-29 CN disclosed
CN-106380729-A Novel PVC heat stablizer 邵卫东 2017-02-08 CN disclosed