SCHEMBL28117862

SCHEMBL28117862

CC(=O)c1sc(NC=O)nc1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.59
SMN1; SMN2 Q16637 6/20 0.59
RXFP1 Q9HBX9 3/20 0.57
CYP1A2 P05177 1/20 0.57
GAA P10253 1/20 0.57
CYP2C9 P11712 1/20 0.57
HPGD P15428 1/20 0.54
RAB9A P51151 7/20 0.51
NPC1 O15118 5/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
MAPT P10636 2/20 0.51
TSHR P16473 2/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
DHODH Q02127 2/20 0.50
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8005543 0.83 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA
SCHEMBL1592594 0.79 RXFP1 (0.62) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA
Hydrochloric Acid SCHEMBL14053819 0.78 RXFP1 (0.60) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA
SCHEMBL4473418 0.78 RXFP1 (0.70) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA
SCHEMBL2835357 0.78 RXFP1 (0.70) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA
SCHEMBL8034351 0.76 RXFP1 (0.58) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA
SCHEMBL2076096 0.75 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA
SCHEMBL4516696 0.75 RXFP1 (0.66) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA
SCHEMBL6410862 0.75 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2RXFP1GAARAB9A
SCHEMBL1911610 0.72 RXFP1 (0.62) ALDH1A1SMN1; SMN2RXFP1CYP1A2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108546254-B 5- (3-phenyl acryloyl) thiazole derivative and preparation method and application thereof 湖南大学 2020-11-24 CN disclosed
CN-108530439-B Furan formamide derivative and preparation method and application thereof 湖南大学 2020-07-21 CN disclosed
CN-106377150-B One kind being based on technology of Internet of things intelligent curtain control system and its working method 江苏建筑职业技术学院 2019-03-29 CN disclosed
CN-106377150-A Intelligent curtain control system based on technology of Internet of things and operation method thereof 江苏建筑职业技术学院 2017-02-08 CN disclosed