Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4210140 | 0.86 | GAA (0.71) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL1720494 | 0.86 | MAPT (0.72) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL12436957 | 0.86 | GAA (0.71) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL3629079 | 0.86 | GAA (0.70) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL14253608 | 0.85 | GAA (0.69) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL5822642 | 0.85 | GAA (1.00) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL7771034 | 0.85 | GAA (0.69) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL5492178 | 0.85 | GAA (0.69) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL27417579 | 0.85 | GAA (0.69) | GAACHRM1ALDH1A1L3MBTL1THRB | |
| SCHEMBL1111736 | 0.83 | GAA (0.67) | GAACHRM1ALDH1A1L3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188043-A | Tetracyclic compound | 梅迪维新技术公司 | 2016-12-07 | — | — | CN | disclosed |