Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL93724 | 1.00 | — | — | |
| Ethane SCHEMBL28247302 | 0.97 | CYP3A4 (0.61) | CYP3A4SLC5A7APEX1NPSR1MEN1 | |
| Water SCHEMBL713765 | 0.97 | CYP3A4 (0.61) | CYP3A4SLC5A7APEX1NPSR1MEN1 | |
| SCHEMBL98070 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28073875 | 0.94 | CYP3A4 (0.58) | CYP3A4SLC5A7APEX1NPSR1MEN1 | |
| Bromide SCHEMBL6153684 | 0.93 | — | — | |
| Fluoride Ion SCHEMBL30462545 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL11059657 | 0.93 | — | — | |
| Water SCHEMBL3860312 | 0.93 | MEN1 (0.56) | CYP3A4SLC5A7APEX1NPSR1MEN1 | |
| SCHEMBL29115129 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102438584-B | The method processing damaged hair | 罗地亚管理公司 | 2016-12-21 | — | — | CN | disclosed |