SCHEMBL28118259

SCHEMBL28118259

O=[C]C(O)c1cccc2ccccc12.[H+]

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP1A2 P05177 2/20 0.48
ADRA2A P08913 2/20 0.42
ADRA2B P18089 2/20 0.42
ADRA2C P18825 2/20 0.42
ADRA1D P25100 2/20 0.42
ADRA1A P35348 2/20 0.42
ADRA1B P35368 2/20 0.42
ACP3 P15309 5/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6405532 0.98 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL1527193 0.78 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL12238420 0.78 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL13134702 0.78 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL12238419 0.78 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL6005210 0.78 ALDH1A1 (0.54) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL30861790 0.77 ALDH1A1 (0.62) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL9950214 0.77 ALDH1A1 (0.62) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL9950211 0.77 ALDH1A1 (0.62) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A
SCHEMBL19514728 0.77 ALDH1A1 (0.62) ALDH1A1CYP2C9CYP2C19CYP1A2ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397115-A Method for preparing alpha-cyperone derivatives 安徽爱有澄生物科技有限公司 2017-02-15 CN disclosed