Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28118260

O=P(O)(Oc1ccccc1)Oc1ccccc1.[N-]=[N+]=[N-].[NH4+]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.59
ALDH1A1 P00352 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
POLB P06746 1/20 0.45
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
GPR84 Q9NQS5 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ANPEP P15144 2/20 0.42
LAP3 P28838 2/20 0.42
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL734215 0.98 SRC (0.61) SRCALDH1A1L3MBTL1TDP1POLB
SCHEMBL59584 0.90 SRC (0.57) SRCALDH1A1L3MBTL1TDP1POLB
Benzene SCHEMBL11142811 0.89 SRC (0.73) SRCALDH1A1L3MBTL1TDP1POLB
SCHEMBL37038 0.89 SRC (0.73) SRCALDH1A1L3MBTL1TDP1POLB
SCHEMBL27676341 0.89 SRC (0.73) SRCALDH1A1L3MBTL1TDP1POLB
SCHEMBL23241864 0.87 SRC (0.70) SRCALDH1A1L3MBTL1TDP1POLB
SCHEMBL150325 0.87 SRC (0.70) SRCALDH1A1L3MBTL1TDP1POLB
SCHEMBL3961989 0.87 SRC (0.70) SRCALDH1A1L3MBTL1TDP1POLB
Water SCHEMBL7104000 0.87 SRC (0.70) SRCALDH1A1L3MBTL1TDP1POLB
SCHEMBL11317985 0.87 SRC (0.70) SRCALDH1A1L3MBTL1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795149-B Double cyclosubstituted benzenesulfonamide derivatives, its preparation method and purposes pharmaceutically 上海海雁医药科技有限公司 2019-09-24 CN disclosed
CN-106243003-B Methanesulfonylbenzamide derivative, its preparation method and the purposes pharmaceutically of cyclic hydrocarbon radical substitution 上海海雁医药科技有限公司 2018-03-09 CN disclosed
CN-106243003-A Cyclic hydrocarbon radical substituted methanesulfonylbenzamide derivant, its preparation method and purposes pharmaceutically 上海海雁医药科技有限公司 2016-12-21 CN disclosed