Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | LAP3 | P28838 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28118260 | 0.98 | SRC (0.59) | SRCALDH1A1L3MBTL1TDP1POLB | |
| SCHEMBL59584 | 0.92 | SRC (0.57) | SRCALDH1A1L3MBTL1TDP1POLB | |
| Benzene SCHEMBL11142811 | 0.91 | SRC (0.73) | SRCALDH1A1L3MBTL1TDP1POLB | |
| SCHEMBL37038 | 0.91 | SRC (0.73) | SRCALDH1A1L3MBTL1TDP1POLB | |
| SCHEMBL27676341 | 0.91 | SRC (0.73) | SRCALDH1A1L3MBTL1TDP1POLB | |
| SCHEMBL23241864 | 0.89 | SRC (0.70) | SRCALDH1A1L3MBTL1TDP1POLB | |
| SCHEMBL3961989 | 0.89 | SRC (0.70) | SRCALDH1A1L3MBTL1TDP1POLB | |
| SCHEMBL11317985 | 0.89 | SRC (0.70) | SRCALDH1A1L3MBTL1TDP1POLB | |
| Water SCHEMBL7104000 | 0.89 | SRC (0.70) | SRCALDH1A1L3MBTL1TDP1POLB | |
| SCHEMBL9583781 | 0.89 | SRC (0.70) | SRCALDH1A1L3MBTL1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912604-A1 | IMPROVED CHEMICAL PROCESS FOR PREPARING AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 | Biosearch Italia S.p.A. (IT) | 1999-05-06 | — | — | EP | claimed |
| WO-1997040067-A1 | IMPROVED CHEMICAL PROCESS FOR PREPARING AMIDE DERIVATIVES OF ANTIBIOTIC A 40926 | BIOSEARCH ITALIA S.P.A. (IT) | 1997-10-30 | — | — | WO | claimed |
| US-5625067-A | Cyclopentane ether derivatives, processes for their production, and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | claimed |
| EP-0558570-B1 | CYCLOPENTANE ETHER DERIVATIVES, METHODS FOR PREPARING THEM AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 1996-01-10 | — | — | EP | claimed |
| EP-4045494-B1 | SYNTHESIS OF 6-METHYL-N1-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)BENZENE-1,3-DIAMINE | ESCO ASTER PTE LTD (SG) | 2023-10-11 | — | — | EP | disclosed |
| US-20230065387-A1 | SYNTHESIS OF TYROSINE KINASE INHIBITORS | ESCO ASTER PTE. LTD (SG) | 2023-03-02 | — | — | US | disclosed |
| WO-2022196528-A1 | 7-OXA-3,4-DIAZABICYCLO[4.1.0]HEPTA-4-ENE-2-ONE COMPOUND AND HERBICIDE | 日本曹達株式会社 | 2022-09-22 | — | — | WO | disclosed |
| EP-4045494-A1 | SYNTHESIS OF 6-METHYL-N1-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)BENZENE-1,3-DIAMINE | Esco Aster Pte. Ltd. (SG) | 2022-08-24 | — | — | EP | disclosed |
| WO-2022161418-A1 | PYRAZOLAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 深圳晶泰科技有限公司 | 2022-08-04 | — | — | WO | disclosed |
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |
| WO-2021115457-A9 | PYRAZOLO[1,5-A]PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳众格生物科技有限公司 | 2022-05-19 | — | — | WO | disclosed |
| WO-2021074138-A1 | SYNTHESIS OF 6-METHYL-N1-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)BENZENE-1,3-DIAMINE | ESCO ASTER PTE. LTD. (SG) | 2021-04-22 | — | — | WO | disclosed |
| EP-0525499-A1 | Amide derivatives of antibiotic A 40926 | GRUPPO LEPETIT S.p.A. (IT) | 1993-02-03 | — | — | EP | disclosed |
| EP-0340245-B1 | SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS | GRUPPO LEPETIT S.p.A. (IT) | 1992-08-19 | — | — | EP | disclosed |
| EP-0465481-A1 | NEW SUBSTITUTED ALKYLAMIDE DERIVATIVES OF TEICOPLANIN. | LEPETIT SPA (IT) | 1992-01-15 | — | — | EP | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |
| WO-1990011300-A1 | NEW SUBSTITUTED ALKYLAMIDE DERIVATIVES OF TEICOPLANIN | GRUPPO LEPETIT S.P.A. (IT) | 1990-10-04 | — | — | WO | disclosed |
| EP-0340245-A1 | SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS. | LEPETIT SPA (IT) | 1989-11-08 | — | — | EP | disclosed |
| WO-1988006600-A1 | SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS | GRUPPO LEPETIT S.P.A. (IT) | 1988-09-07 | — | — | WO | disclosed |
| US-4595677-A | Substituted tetrapeptides | CIBA-GEIGY CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065387-A1 | SYNTHESIS OF TYROSINE KINASE INHIBITORS | ABL1, ROS1, ABL2 | SRC 77/4885ALDH1A1 2173/4885L3MBTL1 1852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.