Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029298 | 0.81 | — | — | |
| SCHEMBL28140618 | 0.78 | XIAP (0.37) | XIAP | |
| Cyclohexane SCHEMBL1535470 | 0.74 | — | — | |
| SCHEMBL28120461 | 0.74 | XIAP (0.31) | XIAP | |
| SCHEMBL17924957 | 0.71 | — | — | |
| SCHEMBL4821010 | 0.71 | LMNA (0.33) | — | |
| SCHEMBL17924861 | 0.70 | — | — | |
| Furan SCHEMBL28420762 | 0.68 | MAPK1 (0.33) | — | |
| SCHEMBL17924886 | 0.68 | — | — | |
| Methylcyclopentane SCHEMBL1535481 | 0.68 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106413756-A | Methods of using anti-STEAP 1 antibodies and immunoconjugates | 豪夫迈·罗氏有限公司 | 2017-02-15 | — | — | CN | disclosed |