Toluene

Toluene

SCHEMBL28118544

Cc1ccccc1.Cc1ccccc1C1(C)CCCCC1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.44
OPRM1 P35372 2/20 0.42
TSHR P16473 2/20 0.41
ALOX12 P18054 2/20 0.41
LMNA P02545 1/20 0.41
ACHE P22303 1/20 0.41
PDE7A Q13946 1/20 0.37
P2RX7 Q99572 1/20 0.36
OPRD1 P41143 1/20 0.36
OPRK1 P41145 1/20 0.36
OPRL1 P41146 1/20 0.36
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28837788 0.94 HDAC4 (0.47) HDAC4OPRM1PDE7AP2RX7OPRD1
SCHEMBL6152617 0.92 HDAC4 (0.49) HDAC4OPRM1TSHRACHEPDE7A
SCHEMBL11800826 0.90 HDAC4 (0.50) HDAC4OPRM1TSHRACHEPDE7A
SCHEMBL11804925 0.80 SLC6A2 (0.39)
SCHEMBL28259692 0.77 HTR2C (0.46) HDAC4
SCHEMBL16033418 0.77 PDE7A (0.42) HDAC4TSHRALOX12PDE7AP2RX7
O-Xylene SCHEMBL27546056 0.75 ACHE (0.65) TSHRALOX12LMNAACHE
SCHEMBL24847523 0.75 PDE7A (0.40) PDE7A
SCHEMBL16037800 0.75 PDE7A (0.40) HDAC4OPRM1TSHRALOX12PDE7A
SCHEMBL5395546 0.75 HDAC4 (0.47) HDAC4OPRM1TSHRACHEPDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414381-A Process for preparing mixtures of dialkylbiphenyl isomers 埃克森美孚化学专利公司 2017-02-15 CN disclosed