SCHEMBL28118610

SCHEMBL28118610

COC(=O)Cc1cc(O)c(O)c(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.58
GAA P10253 2/20 0.49
GFER P55789 2/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 2/20 0.41
F2 P00734 1/20 0.40
F10 P00742 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
THRB P10828 2/20 0.39
POLB P06746 2/20 0.39
LMNA P02545 1/20 0.39
NFKB1 P19838 1/20 0.39
XDH P47989 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29961027 1.00 HSP90AB1 (0.58) HSP90AB1GAAGFERALDH1A1CYP4F2
SCHEMBL2786552 0.91 HSP90AB1 (0.63) HSP90AB1GAAGFERALDH1A1CYP4F2
SCHEMBL8204330 0.87 HSP90AB1 (0.68) HSP90AB1GAAGFERALDH1A1CYP4F2
SCHEMBL31075998 0.87 HSP90AB1 (0.54) HSP90AB1GAAGFERALDH1A1CYP4F2
SCHEMBL7069525 0.85 HSP90AB1 (0.56) HSP90AB1GAAGFERALDH1A1CYP4F2
SCHEMBL7073645 0.83 HSP90AB1 (0.54) HSP90AB1GAAGFERALDH1A1CYP4F2
SCHEMBL1525224 0.83 HSP90AB1 (0.54) HSP90AB1GAAGFERALDH1A1KDM4E
SCHEMBL1302419 0.81 HSP90AB1 (0.51) HSP90AB1GAAGFERALDH1A1CYP4F2
SCHEMBL20599232 0.81 HSP90AB1 (0.51) HSP90AB1GAAGFERALDH1A1CYP4F2
SCHEMBL12678868 0.80 HSP90AB1 (0.58) HSP90AB1GAAGFERALDH1A1CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104341307-B Phenylacetic acid derivatives and anticancer usage thereof 北京京朋汇药业研究发展有限公司 2016-12-28 CN disclosed