Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663470 | 0.96 | AKR1C1 (0.59) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL1622891 | 0.91 | AKR1C1 (0.47) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL28933139 | 0.89 | AKR1C1 (0.45) | AKR1C1HDAC4KMT2AHSD11B1 | |
| SCHEMBL12235292 | 0.81 | AKR1C1 (0.55) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL3068740 | 0.80 | KMT2A (0.52) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL2184245 | 0.79 | AKR1C1 (0.64) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL42114 | 0.75 | AKR1C1 (0.70) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL15866990 | 0.74 | HDAC4 (0.59) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL15866995 | 0.74 | SLC6A4 (0.51) | HDAC4DPP4 | |
| SCHEMBL1667343 | 0.74 | AKR1C1 (0.91) | AKR1C1HDAC4MEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414443-A | Pyridopyrimidinedione derivatives | 诺华股份有限公司 | 2017-02-15 | — | — | CN | disclosed |