SCHEMBL28118711

SCHEMBL28118711

COc1ccc(Cc2ccccc2-c2ccccc2N)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.53
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NSD2 O96028 1/20 0.47
ALDH1A1 P00352 3/20 0.45
HPGD P15428 2/20 0.45
LMNA P02545 1/20 0.45
CYP2D6 P10635 1/20 0.44
ATM Q13315 1/20 0.44
CYP11B1 P15538 3/20 0.44
CYP11B2 P19099 3/20 0.44
ADORA3 P0DMS8 1/20 0.43
MAOB P27338 1/20 0.43
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
MAOA P21397 1/20 0.42
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26949212 0.90 LTA4H (0.64) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL6160843 0.86 LTA4H (0.60) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL28251912 0.80 LTA4H (0.72) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL8766668 0.80 LTA4H (0.61) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL2027109 0.79 LTA4H (0.69) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL30837375 0.76 LTA4H (0.60) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL3902050 0.76 LTA4H (0.60) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL28131751 0.75 LTA4H (0.64) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL18613819 0.75 LTA4H (0.58) LTA4HMEN1KMT2AL3MBTL1NSD2
SCHEMBL6226356 0.75 ABCB1 (0.56) LTA4HMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102884629-B Photosensitive member comprising organic layer 赫里亚泰克有限责任公司 2017-02-08 CN disclosed