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Sugi Predict / Compounds / Dl-Phenylalanine

Dl-Phenylalanine

Dl-Phenylalanine

SCHEMBL28118724

NC(Cc1ccccc1)C(=O)O.O=C(O)C(Cc1ccc(O)cc1)NCc1ccccc1

nearest known ligand 0.65

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 3/20 0.65
▸ ALPI P09923 1/20 0.59
▸ PKM P14618 1/20 0.59
▸ PTGS1 P23219 1/20 0.59
▸ XIAP P98170 1/20 0.59
▸ MME P08473 1/20 0.51
▸ GRIA2 P42262 1/20 0.50
▸ TPH1 P17752 3/20 0.48
▸ ACE P12821 1/20 0.48
▸ OPRD1 P41143 4/20 0.47
▸ OPRM1 P35372 3/20 0.47
▸ OPRK1 P41145 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121370 0.92 MME (0.58) SLC7A5MMEACE
SCHEMBL6065430 0.92 MME (0.58) SLC7A5MMEACE
SCHEMBL6716497 0.92 MME (0.58) SLC7A5MMEACE
SCHEMBL121371 0.92 MME (0.58) SLC7A5MMEACE
SCHEMBL11346818 0.92 MME (0.58) SLC7A5MMEACE
Phenylalanine Methyl Ester SCHEMBL28118728 0.89 SLC7A5 (0.50) SLC7A5MMEOPRD1OPRM1OPRK1
SCHEMBL8414223 0.87 FOLH1 (0.55) SLC7A5MMEACE
SCHEMBL148423 0.87 FOLH1 (0.55) SLC7A5MMEACE
Tyrosine SCHEMBL28049278 0.86 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL5699039 0.85 SLC7A5 (0.89) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106188231-A The synthesis of pasireotide pentapeptide intermediate and application 中国医学科学院药物研究所 2016-12-07 — — CN disclosed