Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.90 |
| ▸ | HPGD | P15428 | 7/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.90 |
| ▸ | CA12 | O43570 | 1/20 | 0.90 |
| ▸ | CA1 | P00915 | 1/20 | 0.90 |
| ▸ | CA2 | P00918 | 1/20 | 0.90 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.90 |
| ▸ | CA4 | P22748 | 1/20 | 0.90 |
| ▸ | CA6 | P23280 | 1/20 | 0.90 |
| ▸ | CA7 | P43166 | 1/20 | 0.90 |
| ▸ | CA9 | Q16790 | 1/20 | 0.90 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.90 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL6029954 | 0.97 | ALDH1A1 (0.95) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL3240193 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL27567475 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL3783483 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL2491526 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29254414 | 0.95 | ALDH1A1 (0.90) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1967 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29360246 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1509155 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29362663 | 0.95 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107136123-A | A kind of sodium alginate for preventing and treating clubroot is coated bacteria agent and preparation method thereof | 明光市农源农作物专业合作社 | 2017-09-08 | — | — | CN | disclosed |
| CN-106173801-A | A kind of efficient compound food fresh keeping preparation | 柳州定店科技有限公司 | 2016-12-07 | — | — | CN | disclosed |