Sugi Predict

Sugi Predict / Compounds / Hydrazine

Hydrazine

Hydrazine

SCHEMBL28119021

NN.O=S(=O)(Cc1ccccc1)N1CCCC1

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.89
▸ HPGD P15428 1/20 0.89
▸ KMT2A Q03164 1/20 0.58
▸ RAB9A P51151 1/20 0.56
▸ ALDH1A1 P00352 5/20 0.56
▸ NPC1 O15118 1/20 0.55
▸ MAPT P10636 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ GAA P10253 1/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6738518 0.96 TSHR (0.96) TSHRHPGDKMT2ARAB9AALDH1A1
SCHEMBL9612077 0.94 TSHR (1.00) TSHRHPGDKMT2ARAB9AALDH1A1
SCHEMBL3936704 0.94 TSHR (1.00) TSHRHPGDKMT2ARAB9AALDH1A1
SCHEMBL735675 0.88 TSHR (0.81) TSHRHPGDKMT2ARAB9AALDH1A1
SCHEMBL1425543 0.81 HPGD (0.66) TSHRHPGDKMT2ARAB9AALDH1A1
SCHEMBL5127258 0.81 TSHR (0.71) TSHRHPGDKMT2ARAB9AALDH1A1
SCHEMBL7239112 0.81 HPGD (0.65) TSHRHPGDKMT2AALDH1A1MAPT
SCHEMBL3912922 0.80 TSHR (0.69) TSHRHPGDKMT2ARAB9AALDH1A1
SCHEMBL656086 0.80 TSHR (0.69) TSHRHPGDKMT2ARAB9AALDH1A1
SCHEMBL4608001 0.80 KMT2A (0.85) TSHRHPGDKMT2ARAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397359-A Preparation method of almotriptan intermediate 4-(1-pyrrolidyl sulfomethyl)-phenylhydrazine 重庆华森制药股份有限公司 2017-02-15 — — CN disclosed