Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 8/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093632 | 0.95 | AKR1B1 (0.44) | AKR1B1THRBCA2KDM4ELMNA | |
| SCHEMBL583915 | 0.83 | AKR1B1 (0.60) | AKR1B1THRBCA2KDM4ELMNA | |
| SCHEMBL11763442 | 0.81 | AKR1B1 (0.48) | AKR1B1THRBCA2KDM4ELMNA | |
| SCHEMBL19202480 | 0.81 | AKR1B1 (0.48) | AKR1B1THRBCA2KDM4ELMNA | |
| SCHEMBL12694824 | 0.80 | GLRA1 (0.32) | — | |
| SCHEMBL7969088 | 0.79 | AKR1B1 (0.54) | AKR1B1CA2KDM4ELMNAGAA | |
| SCHEMBL3182472 | 0.77 | CA2 (0.58) | AKR1B1CA2KDM4ELMNAGAA | |
| SCHEMBL21273844 | 0.76 | CA2 (0.50) | AKR1B1THRBCA2KDM4ELMNA | |
| SCHEMBL15167238 | 0.76 | AKR1B1 (0.48) | AKR1B1THRBCA2KDM4ELMNA | |
| SCHEMBL14511356 | 0.75 | AKR1B1 (0.52) | AKR1B1THRBCA2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257977-B | Composite polyamide membrane post-treated with nitrous acid | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-10-29 | — | — | CN | disclosed |
| CN-106257977-A | Composite polyamide membrane post-treated with nitrous acid | 陶氏环球技术有限责任公司 | 2016-12-28 | — | — | CN | disclosed |