Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095734 | 0.82 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13279903 | 0.77 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7080330 | 0.76 | TSHR (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28822241 | 0.76 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8466813 | 0.72 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10636223 | 0.72 | ESR2 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL850840 | 0.72 | GAA (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12968303 | 0.69 | GABRP (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Ammonia Solution, Strong SCHEMBL11137886 | 0.69 | TSHR (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Cyclopropane Carboxylic Acid SCHEMBL30595491 | 0.69 | TSHR (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111210-B | Condensed imidazole derivatives as IDO inhibitor | 新联基因公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-103547579-B | Fused imidazole derivatives as IDO inhibitors | 新联基因公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-105111210-A | Fused imidazole derivatives useful as IDO inhibitors | NEWLINK GENETICKS CORP | 2015-12-02 | — | — | CN | disclosed |