Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | BMP1 | P13497 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670347 | 0.94 | FPR2 (0.44) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL18041084 | 0.94 | FPR2 (0.44) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL16670307 | 0.90 | FPR2 (0.45) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL16670305 | 0.90 | FPR2 (0.45) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL16669963 | 0.89 | FPR2 (0.45) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL16670196 | 0.89 | FPR2 (0.45) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL16670198 | 0.89 | FPR2 (0.45) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL16669962 | 0.89 | FPR2 (0.45) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL16670530 | 0.89 | POLB (0.51) | FPR2KMT2APTPRBMMP2MMP9 | |
| SCHEMBL16670531 | 0.89 | POLB (0.51) | FPR2KMT2APTPRBMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458940-A | Inhibitors of human immunodeficiency virus replication | 百时美施贵宝公司 | 2017-02-22 | — | — | CN | disclosed |