Atropine

Atropine

SCHEMBL2812

CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1CHRM2CHRM3

The experimentally established mechanism targets of Atropine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 5/20 1.00
CHRM2 known ✓ P08172 5/20 1.00
CHRM3 known ✓ P20309 4/20 1.00
CHRM5 P08912 4/20 1.00
CHRM4 P08173 4/20 1.00
LMNA P02545 3/20 1.00
HTR2C P28335 2/20 1.00
BLM P54132 2/20 1.00
NFKB1 P19838 2/20 1.00
KMT2A Q03164 2/20 1.00
KDM4E B2RXH2 1/20 1.00
MEN1 O00255 1/20 1.00
POLB P06746 1/20 1.00
ADRA2C P18825 1/20 1.00
ADRA1A P35348 1/20 1.00
HRH1 P35367 1/20 1.00
SLC22A1 O15245 1/20 1.00
ADRA1D P25100 1/20 1.00
MAPT P10636 1/20 0.91
ALDH1A1 P00352 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hyoscyamine SCHEMBL41316 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Atropine SCHEMBL41317 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Atropine SCHEMBL17775090 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Atropine SCHEMBL2728129 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Atropine SCHEMBL14946873 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Atropine SCHEMBL8854381 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Atropine SCHEMBL7941966 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Atropine SCHEMBL25020 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Atropine SCHEMBL249586 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4
Hyoscyamine SCHEMBL4957671 1.00 CHRM1 (1.00) CHRM1CHRM2CHRM5CHRM3CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 58243 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6393320-B1 None US claimed
EP-3607938-B1 PHARMACEUTICAL COMPOSITION SOVIC BRKICIC LJILJANA (HR) 2026-05-27 EP claimed
CN-122094664-A An ophthalmically acceptable aqueous liquid composition comprising a muscarinic acetylcholine receptor antagonist 2026-05-26 CN claimed
CN-116850183-B Methods and pharmaceutical compositions for treating myopia GRAND PHARMA (CHINA) Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122075410-A Dry powder composition for intranasal delivery 2026-05-26 CN claimed
US-20260137558-A1 OPHTHALMIC DEVICE Able Tx Ltd. (IL) 2026-05-21 US claimed
US-12629360-B2 Ophthalmic composition Sydnexis, Inc. (US) 2026-05-19 US claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
US-20260131089-A1 DRUG DELIVERY DEVICES AND METHODS FOR ADMINISTERING SUBSTANCES TO A BODY CAVITY BY HETEROGENOUS AEROSOLIZATION FOR TREATMENT OF BINGE-EATING DISORDERS AND/OR OBESITY APTARGROUP, INC. (US) 2026-05-14 US claimed
US-4128651-A Bis-quaternary pyridinium-2-aldoxime salts and a process for their preparation MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1978-12-05 US claimed
US-4107288-A CROSSLINKED MATRIX OF NATURAL POLYMERS, ALDEHYDE HARDENING AGENT, SOLVATING PHARMACEUTICAL SOCIETY OF VICTORIA (AU) 1978-08-15 US claimed
US-4066747-A Polymeric orthoesters housing beneficial drug for controlled release therefrom ALZA CORPORATION (US) 1978-01-03 US claimed
US-4014335-A Ocular drug delivery device ALZA CORPORATION (US) 1977-03-29 US claimed
US-4014334-A Laminated osmotic system for dispensing beneficial agent ALZA CORPORATION (US) 1977-03-29 US claimed
US-4008719-A Osmotic system having laminar arrangement for programming delivery of active agent ALZA CORPORATION (US) 1977-02-22 US claimed
US-3993072-A Microporous drug delivery device ALZA CORPORATION (US) 1976-11-23 US claimed
US-3978201-A BASE FOR OPHTHALMOLOGICAL MEDICINAL PREPARATION ON OPTHALMOLOGICAL MEDICINAL FILM KHROMOV GENNADY LVOVICH 1976-08-31 US claimed
US-3968201-A POLYMER PHARMACIA AKTIEBOLAG (SW) 1976-07-06 US claimed
US-3935303-A Base for ophthalmological medicinal preparations and on ophthalmological medicinal film KHROMOV GENNADY LVOVICH 1976-01-27 US claimed