Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061603 | 0.77 | ELANE (0.43) | SLC22A12ELANEAXLKDM4EMAPT | |
| SCHEMBL28108747 | 0.77 | ELANE (0.43) | SLC22A12ELANEKDM4EMAPTMEN1 | |
| SCHEMBL18633919 | 0.77 | ELANE (0.43) | SLC22A12ELANEAXLKDM4EMAPT | |
| SCHEMBL1892910 | 0.77 | DYRK1A (0.49) | SLC22A12ELANEAXLKDM4EMAPT | |
| SCHEMBL30731192 | 0.77 | DYRK1A (0.49) | SLC22A12ELANEAXLKDM4EMAPT | |
| SCHEMBL12146948 | 0.77 | ELANE (0.43) | SLC22A12ELANEAXLKDM4EMAPT | |
| SCHEMBL20689593 | 0.74 | ELANE (0.45) | SLC22A12ELANEAXLKDM4EMAPT | |
| SCHEMBL19787924 | 0.73 | PDE4A (0.47) | SLC22A12ELANEKDM4EKMT2AALDH1A1 | |
| SCHEMBL20319691 | 0.73 | ELANE (0.41) | SLC22A12ELANEAXLKDM4EMAPT | |
| SCHEMBL28049881 | 0.73 | ELANE (0.57) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432311-A | Processes and intermediates for producing azaindoles | 沃泰克斯药物股份有限公司 | 2017-02-22 | — | — | CN | disclosed |