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Sugi Predict / Compounds / SCHEMBL28121986

SCHEMBL28121986

SCHEMBL28121986

CS(=O)(=O)c1nnc(-c2ccc(Cl)cc2Cl)o1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 10/20 0.56
▸ NPC1 O15118 9/20 0.56
▸ CYP1A2 P05177 2/20 0.56
▸ CYP2C19 P33261 2/20 0.56
▸ SMN1; SMN2 Q16637 9/20 0.54
▸ HPGD P15428 6/20 0.54
▸ ALDH1A1 P00352 5/20 0.54
▸ TP53 P04637 4/20 0.54
▸ HSD17B10 Q99714 4/20 0.54
▸ TSHR P16473 3/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ ALOX15 P16050 2/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CA9 Q16790 1/20 0.52
▸ CA13 Q8N1Q1 1/20 0.52
▸ KDM4E B2RXH2 3/20 0.51
▸ NOTUM Q6P988 1/20 0.51
▸ L3MBTL1 Q9Y468 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9680542 0.81 RAB9A (0.62) RAB9ANPC1SMN1; SMN2HPGDALDH1A1
SCHEMBL11475700 0.80 NPC1 (0.77) RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2
SCHEMBL8590849 0.78 KDM4E (0.60) RAB9ANPC1SMN1; SMN2ALDH1A1TP53
SCHEMBL27857785 0.76 RAB9A (0.59) RAB9ANPC1SMN1; SMN2ALDH1A1TP53
SCHEMBL11482396 0.74 NPC1 (0.73) RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2
SCHEMBL27984899 0.72 PTGER1 (0.47) RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2
SCHEMBL29678498 0.72 NPC1 (0.61) RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2
SCHEMBL11480004 0.72 NPC1 (0.76) RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2
SCHEMBL21451148 0.72 NPC1 (0.61) RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2
SCHEMBL28767347 0.72 NPC1 (0.61) RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109845749-A A kind of composition pesticide for disliking bacterium azoles and tetramycin containing dichloro 佛山市盈辉作物科学有限公司 2019-06-07 — — CN disclosed
CN-109717195-A A kind of bactericidal composition for disliking bacterium azoles and zoxamide containing dichloro 佛山市盈辉作物科学有限公司 2019-05-07 — — CN disclosed
CN-106508944-A Pesticidal composition containing 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole and prochloraz 柳州市惠农化工有限公司 2017-03-22 — — CN disclosed
CN-106508944-A Pesticidal composition containing 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole and prochloraz 柳州市惠农化工有限公司 2017-03-22 — — CN disclosed
CN-106508935-A Pesticide composition containing 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole and mancozeb 柳州市惠农化工有限公司 2017-03-22 — — CN disclosed
CN-106508935-A Pesticide composition containing 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole and mancozeb 柳州市惠农化工有限公司 2017-03-22 — — CN disclosed
CN-106417334-A Bactericide composition containing 2-methylsulfuryl-5-(2, 4-dichlorophenyl)-1, 3, 4-oxadiazole and benthiavalicarb-isopropyl 佛山市普尔玛农化有限公司 2017-02-22 — — CN disclosed
CN-106417334-A Bactericide composition containing 2-methylsulfuryl-5-(2, 4-dichlorophenyl)-1, 3, 4-oxadiazole and benthiavalicarb-isopropyl 佛山市普尔玛农化有限公司 2017-02-22 — — CN disclosed
CN-106386820-A Pesticide composition containing 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole and tebuconazole 柳州市惠农化工有限公司 2017-02-15 — — CN disclosed
CN-106386820-A Pesticide composition containing 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole and tebuconazole 柳州市惠农化工有限公司 2017-02-15 — — CN disclosed
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