Benzene

Benzene

SCHEMBL28122913

C=CC(=O)NCOC.c1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
TGM2 P21980 6/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MTNR1A P48039 2/20 0.35
MTNR1B P49286 2/20 0.35
PSMB11 A5LHX3 1/20 0.35
PSMA7 O14818 1/20 0.35
PSMB1 P20618 1/20 0.35
PSMA1 P25786 1/20 0.35
PSMA2 P25787 1/20 0.35
PSMA3 P25788 1/20 0.35
PSMA4 P25789 1/20 0.35
PSMB8 P28062 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138455 0.94
Ethylene Glycol SCHEMBL9479208 0.88 TSHR (0.48) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL14994951 0.86 TSHR (0.46) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Ethylene Glycol SCHEMBL9479194 0.86 TSHR (0.46) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Glycerin SCHEMBL9477985 0.81 TSHR (0.42) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Glycerin SCHEMBL9477971 0.81 TSHR (0.42) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Triethylene Glycol SCHEMBL9476433 0.80 TSHR (0.41) ALDH1A1TSHRMAPK1TDP1ZDHHC20
Triethylene Glycol SCHEMBL9476444 0.80 TSHR (0.41) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL8219176 0.78 ZDHHC20 (0.50) ALDH1A1TSHRMAPK1TDP1ZDHHC20
SCHEMBL11158435 0.78 TSHR (0.46) ALDH1A1TSHRMAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103819602-B Preparation method for alkali-free glass fiber SMC yarn film-forming agent 北京东方亚科力化工科技有限公司 2017-01-18 CN claimed
CN-106832077-A A kind of ECTFE fluororesin with self-crosslinking structure and preparation method thereof 浙江省化工研究院有限公司 2017-06-13 CN disclosed
CN-103819602-B Preparation method for alkali-free glass fiber SMC yarn film-forming agent 北京东方亚科力化工科技有限公司 2017-01-18 CN disclosed