Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.54 |
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cystine SCHEMBL4267212 | 1.00 | PTGS1 (0.54) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL457219 | 0.87 | PTGS1 (0.73) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL457217 | 0.87 | PTGS1 (0.73) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL457216 | 0.87 | PTGS1 (0.73) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL1983072 | 0.84 | PTGS1 (0.52) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL7442337 | 0.84 | PTGS1 (0.52) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL27890268 | 0.84 | PTGS1 (0.52) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL5018669 | 0.84 | PTGS1 (0.50) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL8332360 | 0.84 | PTGS1 (0.50) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL10225 | 0.84 | PTGS1 (0.50) | PTGS1SLC7A11ARG1ARG2NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106471117-A | Production of heteromultimeric proteins using mammalian cells | 豪夫迈·罗氏有限公司 | 2017-03-01 | — | — | CN | disclosed |