Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.54 |
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cystine SCHEMBL28123296 | 1.00 | PTGS1 (0.54) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL457219 | 0.87 | PTGS1 (0.73) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL457217 | 0.87 | PTGS1 (0.73) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL457216 | 0.87 | PTGS1 (0.73) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL1983072 | 0.84 | PTGS1 (0.52) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL7442337 | 0.84 | PTGS1 (0.52) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL27890268 | 0.84 | PTGS1 (0.52) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL5018669 | 0.84 | PTGS1 (0.50) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL8332360 | 0.84 | PTGS1 (0.50) | PTGS1SLC7A11ARG1ARG2NOS2 | |
| Cystine SCHEMBL10225 | 0.84 | PTGS1 (0.50) | PTGS1SLC7A11ARG1ARG2NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090078384-A1 | Esterases from rumen | HELMHOLTZZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2009-03-26 | — | — | US | disclosed |
| EP-1773991-A2 | NEW ESTERASES FROM RUMEN | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006003009-A2 | NEW ESTERASES FROM RUMEN | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2006-01-12 | — | — | WO | disclosed |
| EP-1614747-A1 | New esterases from rumen | Gesellschaft für Biotechnologische Forschung mbH et al (DE) | 2006-01-11 | — | — | EP | disclosed |
| US-6602700-B1 | Increasing free ferulic acid content of a plant-derived composition using feruloyl esterase of given amino acid sequence; used in food and feed compositions, nutraceuticals and in pulping | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2003-08-05 | — | — | US | disclosed |