4-Nitrotoluene

4-Nitrotoluene

SCHEMBL28124015

Cc1ccc([N+](=O)[O-])cc1.[KH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.95
HSD17B10 Q99714 2/20 0.95
ALDH1A1 P00352 5/20 0.54
TSHR P16473 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
RECQL P46063 1/20 0.54
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
BCHE P06276 1/20 0.53
LMNA P02545 1/20 0.52
MAPK1 P28482 1/20 0.52
PKM P14618 1/20 0.51
KMT2A Q03164 3/20 0.50
RAB9A P51151 2/20 0.50
CYP3A4 P08684 1/20 0.50
CES1 P23141 1/20 0.50
HSP90AA1 P07900 1/20 0.50
CXCR5 P32302 1/20 0.50
APLNR P35414 1/20 0.50
CCR6 P51684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Nitrotoluene SCHEMBL73252 0.97 ACHE (1.00) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL2484690 0.97 ACHE (1.00) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL28481150 0.95 ACHE (0.95) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL29272601 0.95 ACHE (0.95) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL28159293 0.95 ACHE (0.95) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL9734611 0.95 ACHE (0.95) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL6751959 0.95 ACHE (0.95) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL9402408 0.95 ACHE (0.95) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL28533556 0.95 ACHE (0.95) ACHEHSD17B10ALDH1A1TSHRTDP1
4-Nitrotoluene SCHEMBL28284448 0.95 ACHE (0.95) ACHEHSD17B10ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414393-A Diamine compound for liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 东进世美肯株式会社 2017-02-15 CN disclosed