Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.67 |
| ▸ | FYN | P06241 | 2/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938023 | 0.85 | PARP1 (0.65) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL202628 | 0.85 | PARP1 (0.65) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL30442255 | 0.85 | MAOB (0.62) | KMT2AMAOB | |
| SCHEMBL3148484 | 0.85 | KMT2A (0.66) | KMT2A | |
| SCHEMBL3151885 | 0.85 | MAOB (0.62) | KMT2AMAOB | |
| SCHEMBL6356224 | 0.83 | KMT2A (0.47) | PARP1FYNKMT2ACES2CES1 | |
| SCHEMBL3069825 | 0.83 | MRGPRX4 (0.56) | KMT2ACES2CES1 | |
| SCHEMBL2705442 | 0.83 | PARP1 (0.66) | PARP1TNKSPARP15PARP14PARP10 | |
| SCHEMBL3161225 | 0.83 | SMPD1 (0.49) | PARP1KMT2A | |
| SCHEMBL1548903 | 0.82 | KMT2A (0.50) | PARP1KMT2ACES2CES1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458892-B | It is used to prepare a times improved method for carcinomycin prodrug | 斯索恩生物制药有限公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-106458892-A | Improved process for making duocarmycin prodrugs | 斯索恩生物制药有限公司 | 2017-02-22 | — | — | CN | disclosed |