Benzene

Benzene

SCHEMBL28124131

[c]1cccc2ccccc12.c1ccccc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.37
ALOX12 P18054 1/20 0.37
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597746 0.97 CYP2A6 (0.39) CYP2A6ALOX12ALDH1A1TSHRHSD17B10
SCHEMBL35 0.97 CYP2A6 (0.39) CYP2A6ALOX12ALDH1A1TSHRHSD17B10
SCHEMBL20873650 0.94 CYP2A6 (0.37) CYP2A6ALOX12ALDH1A1TSHRHSD17B10
SCHEMBL29094877 0.94 CYP2A6 (0.37) CYP2A6ALOX12ALDH1A1TSHRHSD17B10
SCHEMBL20526418 0.94 CYP2A6 (0.37) CYP2A6ALOX12ALDH1A1TSHRHSD17B10
SCHEMBL6409528 0.94 CYP2A6 (0.37) CYP2A6ALOX12ALDH1A1TSHRHSD17B10
SCHEMBL15969806 0.94 CYP2A6 (0.37) CYP2A6ALOX12ALDH1A1TSHRHSD17B10
Biphenyl SCHEMBL28417976 0.93 ALDH1A1 (0.43) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
SCHEMBL21253156 0.92 CYP2A6 (0.35) CYP2A6ALOX12
SCHEMBL28834554 0.92 CYP2A6 (0.35) CYP2A6ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103874681-B Fungicidal 4-substituted-3-{phenyl[(heterocyclylmethoxy)imino]methyl}-1,2,4-oxadizol-5(4H)-one derivatives 拜耳知识产权有限责任公司 2017-01-18 CN claimed