Crotonic Acid

Crotonic Acid

SCHEMBL28124164

C=CC(=O)OCCC(=O)OC.CC=CC(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 5/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 1/20 0.42
LMNA P02545 1/20 0.40
HCAR2 Q8TDS4 6/20 0.39
THRB P10828 2/20 0.36
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1673552 0.87 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12270514 0.81 TSHR (0.46) TSHRALDH1A1HSD17B10LMNAHCAR2
Crotonic Acid SCHEMBL9681122 0.80 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A
Crotonic Acid SCHEMBL9681135 0.80 TSHR (0.68) TSHRHPGDALDH1A1TP53HIF1A
Crotonic Acid SCHEMBL28089691 0.78 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
Crotonic Acid SCHEMBL9511122 0.78 TSHR (0.73) TSHRHPGDALDH1A1TP53HIF1A
Crotonic Acid SCHEMBL27635748 0.78 TSHR (0.53) TSHRHPGDALDH1A1TP53HIF1A
Acrylic Acid Methyl Ester SCHEMBL27534187 0.77 HCAR2 (0.54) TSHRHPGDALDH1A1TP53HIF1A
Crotonic Acid SCHEMBL28156701 0.77 HCAR2 (0.54) TSHRHPGDALDH1A1TP53HIF1A
Crotonic Acid SCHEMBL28122010 0.77 TSHR (0.58) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459302-A UV curable acrylic copolymers 汉高股份有限及两合公司 2017-02-22 CN claimed
CN-106459313-A Curable adhesive compositions and use thereof 汉高知识产权控股有限责任公司 2017-02-22 CN disclosed