Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Crotonic Acid SCHEMBL9681135 | 1.00 | TSHR (0.68) | TSHRHPGDALDH1A1TP53HIF1A | |
| Crotonic Acid SCHEMBL27635748 | 0.90 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| Crotonic Acid SCHEMBL28089691 | 0.90 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| Maleic Acid SCHEMBL956148 | 0.89 | TSHR (0.79) | TSHRHPGDALDH1A1TP53HIF1A | |
| Fumaric Acid SCHEMBL30592706 | 0.89 | TSHR (0.79) | TSHRHPGDALDH1A1TP53HIF1A | |
| Fumaric Acid SCHEMBL956152 | 0.89 | TSHR (0.79) | TSHRHPGDALDH1A1TP53HIF1A | |
| Crotonic Acid SCHEMBL21436776 | 0.88 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29132468 | 0.85 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| Propene SCHEMBL8850804 | 0.85 | TSHR (0.86) | TSHRHPGDALDH1A1TP53HIF1A | |
| Propene SCHEMBL10529480 | 0.85 | TSHR (0.86) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130395-A | Butadiene and vinyl monomer copolymers | PENFORD PRODUCTS COMPANY (US) | 1992-07-14 | — | — | US | disclosed |