⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018640 | 0.91 | — | — | |
| SCHEMBL826133 | 0.69 | — | — | |
| SCHEMBL12018641 | 0.69 | — | — | |
| SCHEMBL12825196 | 0.69 | — | — | |
| SCHEMBL14074203 | 0.66 | APLNR (0.32) | — | |
| SCHEMBL10036450 | 0.66 | — | — | |
| SCHEMBL12018611 | 0.65 | — | — | |
| SCHEMBL13417723 | 0.65 | — | — | |
| SCHEMBL18373673 | 0.65 | — | — | |
| SCHEMBL2781558 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459034-B | Carbostyril derivative as fibroblast growth factor acceptor inhibitor | 普林斯匹亚生物制药公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-106459034-A | Quinolone derivatives as fibroblast growth factor receptor inhibitors | 普林斯匹亚生物制药公司 | 2017-02-22 | — | — | CN | disclosed |