SCHEMBL28124184

SCHEMBL28124184

CN(C)[SiH3].Nc1ccc(N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 10/20 0.58
CYP3A4 P08684 10/20 0.58
ALDH1A1 P00352 9/20 0.58
MAPK1 P28482 5/20 0.58
ALOX15 P16050 3/20 0.58
TP53 P04637 2/20 0.58
MAPT P10636 3/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ACHE P22303 1/20 0.50
TSHR P16473 5/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
GFER P55789 2/20 0.43
PSMD14 O00487 1/20 0.43
RECQL P46063 1/20 0.43
HSD17B10 Q99714 2/20 0.42
CA3 P07451 1/20 0.42
THRB P10828 1/20 0.42
CA6 P23280 1/20 0.42
CASP1 P29466 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL10350684 0.85 MAPT (0.67) TDP1CYP3A4ALDH1A1MAPK1ALOX15
Trimethylammonium SCHEMBL27849651 0.81 MAPT (0.61) TDP1CYP3A4ALDH1A1MAPK1ALOX15
SCHEMBL320609 0.76 MEN1 (1.00) TDP1CYP3A4ALDH1A1MAPK1ALOX15
SCHEMBL27981 0.76
SCHEMBL15246 0.73 ALDH1A1 (1.00) TDP1CYP3A4ALDH1A1MAPK1ALOX15
SCHEMBL21474106 0.73 ALDH1A1 (0.68) TDP1CYP3A4ALDH1A1MAPK1ALOX15
SCHEMBL64766 0.73 ALDH1A1 (0.68) TDP1CYP3A4ALDH1A1MAPK1ALOX15
SCHEMBL8468934 0.73 ALDH1A1 (1.00) TDP1CYP3A4ALDH1A1MAPK1ALOX15
SCHEMBL7877908 0.73 ALDH1A1 (0.68) TDP1CYP3A4ALDH1A1MAPK1ALOX15
Methyl Alcohol SCHEMBL9437744 0.72 MAPT (0.73) TDP1CYP3A4ALDH1A1MAPK1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459407-A Polyamide 株式会社可乐丽 2017-02-22 CN disclosed