Octrizole

Octrizole

SCHEMBL28124262

CC(C)(C)CC(C)(C)c1ccc(O)c(-n2nc3ccccc3n2)c1.O=C(c1ccccc1)c1cccc(O)c1O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
MAPT P10636 3/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 2/20 0.35
ALOX12 P18054 1/20 0.35
RECQL P46063 1/20 0.35
HSD17B14 Q9BPX1 1/20 0.34
MAPK1 P28482 3/20 0.33
USP2 O75604 2/20 0.33
CYP3A4 P08684 2/20 0.33
PGR P06401 2/20 0.33
SLC6A2 P23975 2/20 0.33
PDE4A P27815 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octrizole SCHEMBL28983126 0.83 NPC1 (0.56) NPC1RAB9ALMNAMEN1KMT2A
Octrizole SCHEMBL15508 0.83 NPC1 (0.56) NPC1RAB9ALMNAMEN1KMT2A
Octrizole SCHEMBL29349945 0.83 NPC1 (0.56) NPC1RAB9ALMNAMEN1KMT2A
Octrizole SCHEMBL30315837 0.82 NPC1 (0.55) NPC1RAB9ALMNAMEN1KMT2A
Octrizole SCHEMBL8614902 0.81 NPC1 (0.51) NPC1RAB9ALMNAMEN1KMT2A
Octrizole SCHEMBL28295697 0.81 HPGD (0.46) NPC1RAB9ALMNAMAPTALDH1A1
Octrizole SCHEMBL5072028 0.81 NPC1 (0.46) NPC1RAB9ALMNAMEN1KMT2A
Octrizole SCHEMBL5547097 0.80 NPC1 (0.52) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL8390136 0.79 NPC1 (0.49) NPC1RAB9ALMNAMEN1KMT2A
Octrizole SCHEMBL12076352 0.78 NPC1 (0.68) NPC1RAB9ALMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104260519-B A self-cooling type photovoltaic backboard and a preparing method thereof 中天光伏材料有限公司 2017-01-18 CN claimed
CN-104260519-B A self-cooling type photovoltaic backboard and a preparing method thereof 中天光伏材料有限公司 2017-01-18 CN disclosed