Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octrizole SCHEMBL29349945 | 0.96 | NPC1 (0.56) | NPC1RAB9ALMNACYP2D6CYP3A4 | |
| Octrizole SCHEMBL15508 | 0.96 | NPC1 (0.56) | NPC1RAB9ALMNACYP2D6CYP3A4 | |
| Octrizole SCHEMBL28983126 | 0.96 | NPC1 (0.56) | NPC1RAB9ALMNACYP2D6CYP3A4 | |
| Octrizole SCHEMBL30315837 | 0.95 | NPC1 (0.55) | NPC1RAB9ALMNACYP2D6CYP3A4 | |
| Octrizole SCHEMBL8614902 | 0.91 | NPC1 (0.51) | NPC1RAB9ALMNACYP2D6CYP3A4 | |
| Octrizole SCHEMBL12076352 | 0.90 | NPC1 (0.68) | NPC1RAB9ALMNACYP2D6CYP3A4 | |
| SCHEMBL78159 | 0.89 | NPC1 (0.64) | NPC1RAB9ALMNACYP2D6MEN1 | |
| SCHEMBL29354646 | 0.89 | NPC1 (0.64) | NPC1RAB9ALMNACYP2D6MEN1 | |
| SCHEMBL8390136 | 0.89 | NPC1 (0.49) | NPC1RAB9ALMNACYP2D6CYP3A4 | |
| Octrizole SCHEMBL5072028 | 0.86 | NPC1 (0.46) | NPC1RAB9ALMNACYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2505323-B1 | Composition for treating wood | BERKEM SA (FR) | 2014-02-26 | — | — | EP | disclosed |
| EP-2505323-A1 | Composition for treating wood | Berkem (FR) | 2012-10-03 | — | — | EP | disclosed |
| EP-1765878-A1 | PROCESS FOR PHOTOCURING WITH LIGHT EMITTING DIODES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005100408-A1 | PROCESS FOR PHOTOCURING WITH LIGHT EMITTING DIODES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |
| US-6586606-B2 | By hydrolyzing the corresponding 2-aminobenzofuran; use as stabilizer against oxidative, thermal, or light-induced degradation in lubricants, fuels, polymers, and hydraulic or metal working fluids | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |
| US-20020115855-A1 | Process for the preparation of 3-aryl-benzofuran-2-ones | CIBA SPECIALTY CHEMICALS CORP. | 2002-08-22 | — | — | US | disclosed |
| US-20020087000-A1 | Oligomeric hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same | CYTEC TECHNOLOGY CORP. | 2002-07-04 | — | — | US | disclosed |
| US-5616637-A | PHOTOSTABILITY; OXIDTION AND HEAT RESISTANT | CIBA-GEIGY CORPORATION (US) | 1997-04-01 | — | — | US | disclosed |
| US-5614572-A | Benzofuran-2-ones as stabilizers | CIBA-GEIGY CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5478875-A | Reaction product of glycols or alcohols with vegetable oil and aromatic alcohol ester derivative; used in lubricants and polymers | CIBA-GEIGY CORPORATION (US) | 1995-12-26 | — | — | US | disclosed |
| US-5463058-A | Light, heat and oxidation stabilizers for synthetic polymers | CIBA-GEIGY CORPORATION (US) | 1995-10-31 | — | — | US | disclosed |
| US-5442067-A | Photostability, heat resistance, oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| US-5405891-A | Hindered amine light stabilizers | CIBA-GEIGY CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5369159-A | Heat, oxidation and radiation resistance for polymers | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115855-A1 | Process for the preparation of 3-aryl-benzofuran-2-ones | CYP1B1, CYP1A1, SULT1A1 | NPC1 3095/4885RAB9A 4232/4885LMNA 1505/4885 |
| US-20020087000-A1 | Oligomeric hindered amine light stabilizers based on multi-functional carbonyl compounds and methods of making same | CBR1, CCNE2, NAF1 | NPC1 1993/4885RAB9A 2137/4885LMNA 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.