SCHEMBL28124343

SCHEMBL28124343

C=Cc1cccc(C(N)=O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 3/20 0.41
KDM4E B2RXH2 4/20 0.41
BCAT2 O15382 1/20 0.39
ALDH1A1 P00352 5/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 2/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
LMNA P02545 2/20 0.37
PLK4 O00444 1/20 0.37
CHEK1 O14757 1/20 0.37
AURKA O14965 1/20 0.37
DAPK3 O43293 1/20 0.37
MAP4K4 O95819 1/20 0.37
CSF1R P07333 1/20 0.37
RET P07949 1/20 0.37
FGFR1 P11362 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5279852 0.89 PARP1 (0.43) PARP1KDM4EBCAT2ALDH1A1HPGD
SCHEMBL30259474 0.87 ALDH1A1 (0.44) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL674718 0.87 ALDH1A1 (0.44) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL30382166 0.87 ALDH1A1 (0.44) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL29101464 0.85 ALDH1A1 (0.43) KDM4EALDH1A1HPGDMAPTTSHR
Phthalic Acid SCHEMBL28882077 0.84 ALDH1A1 (0.52) KDM4EALDH1A1HPGDMAPTHSD17B10
Acetic Acid SCHEMBL1234610 0.82 ALDH1A1 (0.40) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL8844181 0.80 ALDH1A1 (0.50) PARP1KDM4EBCAT2ALDH1A1HPGD
SCHEMBL1004375 0.79 ALDH1A1 (0.50) PARP1KDM4EBCAT2ALDH1A1HPGD
SCHEMBL28023544 0.78 TSHR (0.43) KDM4EALDH1A1MAPTTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694655-A Adhesive sheet and display body 琳得科株式会社 2019-04-30 CN disclosed
CN-107239008-A Image processing system and handle box 富士施乐株式会社 2017-10-10 CN disclosed
CN-106459631-A Aqueous resin based ink jet inks 爱克发印艺公司 2017-02-22 CN disclosed
CN-106459630-A Aqueous resin based inkjet inks 爱克发印艺公司 2017-02-22 CN disclosed