Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711035 | 0.86 | CA1 (0.73) | CA1CA2ALDH1A1HDAC3HDAC1 | |
| SCHEMBL27960517 | 0.84 | HIF1A (0.52) | CA1CA2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL28123909 | 0.83 | CA1 (0.59) | CA1CA2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL18415526 | 0.82 | CA1 (1.00) | CA1CA2ALDH1A1TSHRHDAC3 | |
| SCHEMBL5068509 | 0.78 | CA1 (0.75) | CA1CA2ALDH1A1HSD17B10HDAC3 | |
| SCHEMBL9183136 | 0.78 | TSHR (1.00) | ALDH1A1TSHRHSD17B10TDP1HIF1A | |
| Benzene SCHEMBL9464161 | 0.78 | TSHR (1.00) | ALDH1A1TSHRHSD17B10TDP1HIF1A | |
| Hydrogen Peroxide SCHEMBL29071816 | 0.78 | TSHR (1.00) | ALDH1A1TSHRHSD17B10TDP1HIF1A | |
| SCHEMBL22820 | 0.78 | TSHR (1.00) | ALDH1A1TSHRHSD17B10TDP1HIF1A | |
| SCHEMBL28771784 | 0.77 | TDP1 (0.96) | ALDH1A1TSHRHSD17B10TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458873-A | sulfonamide compounds and their use as STAT5 inhibitors | 多伦多大学管理委员会 | 2017-02-22 | — | — | CN | disclosed |