Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | MASP2 | O00187 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374296 | 0.84 | HPGD (0.64) | POLBMAPTTDP1LMNACCR6 | |
| SCHEMBL8107182 | 0.81 | L3MBTL1 (0.56) | MAPTTDP1LMNAL3MBTL1HPGD | |
| SCHEMBL31512634 | 0.81 | ESRRA (0.44) | POLBMAPTTDP1LMNAMASP2 | |
| SCHEMBL10980033 | 0.81 | MAPT (0.61) | POLBMAPTTDP1LMNACCR6 | |
| SCHEMBL11189597 | 0.80 | MAPT (0.61) | POLBMAPTTDP1LMNACCR6 | |
| SCHEMBL29084580 | 0.79 | HPGD (0.64) | POLBTDP1LMNAL3MBTL1HPGD | |
| SCHEMBL8091743 | 0.79 | HPGD (0.60) | POLBMAPTTDP1LMNAL3MBTL1 | |
| SCHEMBL643370 | 0.79 | POLB (0.64) | POLBMAPTTDP1LMNACCR6 | |
| SCHEMBL30740405 | 0.79 | POLB (0.64) | POLBMAPTTDP1LMNACCR6 | |
| SCHEMBL30811573 | 0.78 | MAPT (0.60) | POLBMAPTTDP1LMNACCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336380-B | Pyrazole amide compound containing diphenyl ether structure, preparation method and application thereof | 浙江省化工研究院有限公司 | 2020-03-17 | — | — | CN | disclosed |
| CN-106336380-A | Diphenyl ether structure-containing pyrazolecarboxamide compound and its preparation method and use | 浙江省化工研究院有限公司 | 2017-01-18 | — | — | CN | disclosed |