Carbazole

Carbazole

SCHEMBL28124707

B.c1ccc2c(c1)[nH]c1ccccc12.c1ccccc1

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.88
GPR3 P46089 2/20 0.88
HSD17B10 Q99714 2/20 0.88
AHR P35869 2/20 0.70
KDM4E B2RXH2 3/20 0.62
LMNA P02545 2/20 0.62
HPGD P15428 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
GLA P06280 1/20 0.62
GAA P10253 1/20 0.62
HTT P42858 1/20 0.62
ATM Q13315 1/20 0.62
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
TNKS O95271 1/20 0.56
CYP1A2 P05177 1/20 0.56
PARP1 P09874 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
PARP15 Q460N3 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbazole SCHEMBL27849637 0.97 ALDH1A1 (0.93) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL21060997 0.97 ALDH1A1 (0.93) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL7079222 0.97 ALDH1A1 (0.93) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL38829 0.97 ALDH1A1 (0.93) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL27801512 0.94 ALDH1A1 (0.88) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL28359792 0.94 ALDH1A1 (0.88) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL29355407 0.94 ALDH1A1 (1.00) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL29627417 0.94 ALDH1A1 (1.00) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL30761795 0.94 ALDH1A1 (1.00) ALDH1A1GPR3HSD17B10AHRKDM4E
Carbazole SCHEMBL30209164 0.94 ALDH1A1 (1.00) ALDH1A1GPR3HSD17B10AHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106432200-A Main body material for organic electroluminescent devices 中国科学院苏州纳米技术与纳米仿生研究所 2017-02-22 CN disclosed